Manchester United vs. Liverpool odds, picks and prediction

Nathan Beighle
Sportsbook Wire

In the most anticipated EPL game of the weekend, Liverpool (5 wins, 0 losses, 3 draws) will visit Manchester United (4-2-2). Kickoff from Old Trafford is set for 11:30 a.m. ET. Below, we preview the Manchester United vs. Liverpool odds and lines, and make our best EPL bets, picks and predictions.

Liverpool could be the most balanced club in the EPL, with a talented attacking trio and arguably the best defender in the world, 30-year-old D Virgil van Dijk. The undefeated club will be a road favorite Sunday.

The Reds' attack is led by star F Mohamed Salah, who had the league's most goals entering the weekend. F Roberto Firmino and F Sadio Mane both rank in the top ten in goals scored as well.

Manchester United will have its hands full, especially because it looks likely it will not have F Bruno Fernandes or F Marcus Rashford available. Midseason addition F Cristiano Ronaldo and M Paul Pogba will have their work cut out.

Man U was thrashed 4-2 by Leicester City last weekend in EPL action but picked up a 3-2 mid-week victory over Atalanta in the Champions League.

Manchester United vs. Liverpool: Odds, picks and predictions

Odds provided by Tipico Sportsbook ; access USA TODAY Sports' betting odds for a full list. Lines last updated Saturday at 1 p.m. ET.

  • Money line: Manchester United +195 (bet $100 to win $195) | Liverpool +127 (bet $100 to win $127) | Draw +270
  • Over/Under: 3.5 (O: +125 | U: -160)

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Prediction

Liverpool 2, Manchester United 0

Money line (ML)

BET on LIVERPOOL (+127) as the best bet in this match.

Liverpool has shown far fewer flaws so far this season despite both sides having ultra-talented players. Man U is inconsistent in its play as we've seen over the last week.

While United should be better at home, Liverpool will more than likely prove to be too much. The Reds come into the weekend with the most goals in the EPL and their attacking trio is in great form, and they've only given up 6 goals in 8 games.

Manchester United has tied Everton, lost to Aston Villa and lost to Leicester in its last three EPL matches. Even at home against a surging Liverpool, it stands little chance of even a draw.

Over/Under (O/U)

"LEAN" to the ALTERNATE TOTALUNDER 2.5 (+145).

Why? Because there are typically fewer goals in massive EPL matches.

Both Chelsea and Liverpool lead the league in scoring, yet it resulted in a 1-1 draw when they played. Even when Liverpool took on Manchester City, despite 4 goals being scored, there were just 7 total shots on goal.

Last season, Man U and Liverpool had two of the top-five scoring offenses. However, in their head-to-head matches, Liverpool won one 2-0 and the other was a 1-1 draw.

With van Dijk looking to play all 90, expect Man U's defense to be energized at home. Down key strikers, their offense may not have the same fortune.

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