At least one other Chiefs regular won't start on Sunday at Denver.
Wide receiver/return specialist Tyreek Hill was listed as out by the Chiefs because of a death in his family.
Hill's regular season ends with 75 receptions for 1,183 yards and seven receiving touchdowns. He is averaging 8.2 yards per punt return with one touchdown and was chosen to the Pro Bowl as a return specialist and alternate as a wide receiver. He hadn't missed a game in his two-year career.
Earlier in the week, Andy Reid announced rookie Patrick Mahomes would start at quarterback over Alex Smith.
Defensive tackle Bennie Logan is listed as doubtful because of a knee injury. He was among several players who didn't practice on Friday but several others were out because of what Andy Reid described as a flu that has gone around the team.
Listed as questionable because of illness are offensive lineman Cameron Irving, running back Charcandrick West, defensive end Rakeem Nunez-Roches and cornerback Kenneth Acker.
Linebacker Kevin Pierre-Louis and running back Akeem Hunt are dealing with shoulder injuries and are listed as questionable, as is linebacker Tamba Hali (knee).
The Broncos list three players out: wide receiver Emmanuel Sanders, wide receiver Cody Latimer and defensive end Zach Kerr.
Former Chiefs tackle Donald Stephenson is listed as questionable for the Broncos because of a hand injury.